![]() For improved reproducibility and repeatability of liver PDFF and R2* measurements, clinicians and researchers should sample as much area of the liver as possible using multiple large ROIs. ![]() This approach was the most time-burdensome, requiring a mean ± SD of 149.7 ± 8.6 s per dataset.ĬONCLUSION. Intrare-viewer agreement was ± 2.6 s −1 for cohort A and ± 14.6 s −1 for cohort B. ![]() For R2* interre-viewer agreement had mean LOA of ± 3.0 s −1 for cohort A and ± 17.9 s −1 for cohort B. Intrareviewer agreement was ± 0.5% for cohort A and ± 0.9% for cohort B. For PDFF, interreviewer agreement had mean LOA of ± 0.8% for cohort A and ± 1.7% for cohort B. Averaging largest-fit ROIs over the nine Couinaud segments resulted in the narrowest limits of agreement (LOA) for liver PDFF and R2* measurements in both cohorts. Inter- and intrareviewer agreement of liver PDFF and R2* were evaluated using Bland-Altman analysis. Three reviewers measured liver PDFF and R2* using previously reported ROI sampling strategies. Cohort B included 37 patients with suspected liver iron overload. Cohort A included 53 patients referred for abdominal MRI and healthy subjects recruited for a comparison study of CT and MRI. CSE data from two cohorts were retrospectively analyzed. ![]() A secondary purpose was to standardize ROI-based liver PDFF and R2* measurements by providing a compromise between measurement reproducibility and repeatability and time burden for image analysts. The purpose of this study was to evaluate the reproducibility (interreviewer agreement) and repeatability (intrareviewer agreement) of ROI sampling strategies to measure chemical shift–encoded (CSE) MRI-based liver proton density fat fraction (PDFF) and R2* (1 / T2*). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |